Skip to main content
Fig. 3 | Cancer Cell International

Fig. 3

From: CircMMP11 regulates proliferation, migration, invasion, and apoptosis of breast cancer cells through miR-625-5p/ZEB2 axis

Fig. 3

Suppression of ZEB2 inhibited proliferation, migration, and invasion while induced apoptosis of breast cancer cells. ak MCF-7 and MDA-MB-231 cells were transfected with si-NC or si-ZEB2. a, b The expression of ZEB2 was detected by RT-qPCR assay in MCF-7 and MDA-MB-231 cells. ce MTT and colony-forming assays were performed in MCF-7 and MDA-MB-231 cells. f, g The migration and invasion of MCF-7 and MDA-MB-231 cells were assessed by transwell assay. h The apoptosis was examined by flow cytometry assay. ik The western blot assay was used to test protein expression of E-cadherin and Vimentin in MCF-7 and MDA-MB-231 cells. **P < 0.01, ***P < 0.001

Back to article page