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Fig. 2 | Cancer Cell International

Fig. 2

From: LINC00221 silencing prevents the progression of hepatocellular carcinoma through let-7a-5p-targeted inhibition of MMP11

Fig. 2

Suppression of LINC00221 inhibits cell viability and cell cycle entry while enhancing cell apoptosis in HCC (Huh7 and MHCC97-H) cells. a viability of Huh7 and MHCC97-H cells upon LINC00221 silencing or overexpression assessed by MTT assay. B-C, cell cycle distribution in Huh7 (b) and MHCC97-H (c) cells upon LINC00221 silencing or overexpression examined by flow cytometry. D-E, the apoptosis in Huh7 (d) and MHCC97-H (e) cells after silencing or overexpression of LINC00221 examined by flow cytometry. Cell experiments were independently repeated 3 times. *p < 0.05 vs. the si-NC group; #p < 0.05 vs. the oe-NC group. Comparison among multiple groups was made using one-way ANOVA with Tukey’s post hoc test while data at different time points were compared using two-way ANOVA with Bonferroni post hoc test

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Cancer Cell International

ISSN: 1475-2867

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