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Fig. 5 | Cancer Cell International

Fig. 5

From: miR-129-5p inhibits clear cell renal cell carcinoma cell proliferation, migration and invasion by targeting SPN

Fig. 5

miR-129-5p targets SPN to regulate ccRCC cell malignant progression. a The mRNA expression and b protein expression of SPN in miR-NC + oe-NC, miR-NC + oe-SPN and miR-mimics + oe-SPN groups; c Cell proliferative ability, d colony forming ability, e cell invasive and f migratory abilities were detected by CCK-8 assay, colony formation assay, Transwell assay (100×) and wound healing assay (40×), respectively; g Cell cycle analyzed via flow cytometry; h Cell apoptosis evaluated by flow cytometry; * represents comparison with the miR-NC + oe-NC group, p < 0.05; # represents comparison with the miR-NC + oe-SPN group, p < 0.05

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Cancer Cell International

ISSN: 1475-2867

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