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Fig. 3 | Cancer Cell International

Fig. 3

From: Long non-coding RNA LINC00470 in serum derived exosome: a critical regulator for proliferation and autophagy in glioma cells

Fig. 3

Exosomes from serum of glioma patients affected tumor formation in nude mouse. Note: In vivo imaging analyzed fluorescence intensity in brains of nude mice (a). H&E staining showing the morphology of mice injected with serum exosomes of glioma patients (b). IHC staining was performed to measure the expression of Ki67 (c). Western blotting was used to detect the expressions of autophagy related proteins (LC3-II/LC3-I, Beclin1 and p62) as well as WEE1 expression (d) and PI3K/AKT/mTOR pathway related proteins (e). * P < 0.05, ** P < 0.01, *** P < 0.001, compared to HC-exo group. GBM-exo, exosomes derived from patients with glioma; H&E, Hematoxylin eosin; IHC, immunohistochemistry

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Cancer Cell International

ISSN: 1475-2867

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