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Fig. 8 | Cancer Cell International

Fig. 8

From: Long non-coding RNA LINC00470 in serum derived exosome: a critical regulator for proliferation and autophagy in glioma cells

Fig. 8

Activation of PI3K/AKT/mTOR pathway inhibited autophagy of glioma cells. Note: miR-580-3p, WEE1 or LINC00470 was overexpressed or inhibited in U251 and SWO-38 cells, and then Western blotting was used to assess the expression levels of PI3K/AKT/mTOR pathway related proteins (a) as well as p-PI3K/PI3K (b), p-AKT/AKT (c), and p-mTOR/mTOR (d). * P < 0.05, ** P < 0.01, compared to Control group. # P < 0.05, ## P < 0.01, compared to miR-580-3p mimic group; GBM-exo, exosomes derived from patients with glioma

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