Table 3 Univariate and multivariate analyses of prognostic factors for DFS in gastric cancer
Variable | DFS | |||
|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
P value | HR (95% CI) | P value | HR (95% CI) | |
Age (yr) | 0.369 | 0.722 (0.355–1.470) | ||
≤ 50 vs > 50 | ||||
Gender | 0.784 | 1.092 (0.581–2.054) | ||
Male vs female | ||||
Tumor diameter (cm) | 0.001** | 2.999 (1.612–5.577) | 0.228 | 1.536 (0.765–3.086) |
≤ 4 vs > 4 | ||||
Tumor location | 0.693 | 0.877 (0.457–1.681) | ||
Up + Middle vs Down | ||||
Tumor differentiation | 0.043* | 1.895 (1.021–3.515) | 0.353 | 1.361 (0.710–2.610) |
High + Middle vs Low | ||||
CEA (ng/ml) | 0.135 | 1.755 (0.839–3.672) | ||
≤ 5 vs > 5 | ||||
CA 19-9 (U/ml) | 0.845 | 0.926 (0.429–2.000) | ||
≤ 37 vs > 37 | ||||
HP infection | 0.746 | 0.905 (0.494–1.658) | ||
− vs + | ||||
T stage | 0.002** | 3.270 (1.561–6.849) | 0.724 | 0.842 (0.325–2.184) |
T1-2 vs T3-4 | ||||
N stage | < 0.0001**** | 7.548 (3.324–17.140) | 0.017* | 3.188 (1.235–8.230) |
N0 vs N1-3 | ||||
HOXA-AS3 in tissues | < 0.0001**** | 7.462 (3.420–16.283) | 0.005** | 4.014 (1.534–10.508) |
High vs Low | ||||