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Fig. 4 | Cancer Cell International

Fig. 4

From: Identification of key genes involved in tumor immune cell infiltration and cetuximab resistance in colorectal cancer

Fig. 4

Identification of common DEGs and construction of PPI network. a, b Identification of DEGs between the resistant (red) and sensitive (blue) groups from the GSE5851 and GSE59857 datasets, illustrated by a heat map. Each column is a sample and each row is a gene. c The venn diagram shows the intersection of DEGs among GSE5851, GSE59857 and CACO2-CR cellular model. d The Network diagram illustrates the interactions of common DEGs. e The PPI network including 12 DEGs and recognized cetuximab resistance-related genes from the Genomics of Drug Sensitivity in Cancer database. DEGs: Differentially expressed genes. PPI: protein-protein interaction network

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