Fig. 4

Screening and validation of hub genes. a, b Univariate and multivariate analysis of overall survival rate of ccRCC patients. c–h Tissue expression difference analysis and survival analysis of three hub genes based on the TCGA cohort. i TEK mRNA expression difference was analyzed based on GSE53757 dataset. j Correlation analysis between TEK and pathological stages (based on GSE53757 dataset). k, l Analyze the differential expression of TEK in tumor and adjacent tissues by qPCR and IHC experiments