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Table 1 The association between FZD2 expression and clinical-pathological characteristics in breast cancers

From: FZD2 promotes TGF-β-induced epithelial-to-mesenchymal transition in breast cancer via activating notch signaling pathway

Expression of FZD2

Factors

Low (N = 71)

High (N = 34)

P-value

Age (years)

 ≤ 50

35

17

1

 > 50

36

17

 

Tumor size (cm)

 < 2.5

31

22

0.060

 ≥ 2.5

40

12

 

ER status

 (+)

35

23

0.095

 (−)

36

11

 

PR status

 (+)

44

20

0.832

 (−)

27

14

 

Her-2 status

 (+)

22

13

0.511

 (−)

49

21

 

Ki-67 status (%)

 ≤ 20%

24

10

0.824

 > 20%

47

24

 

Pathological grading

 I–II

51

23

0.655

 III

20

11

 

TNM stage

 I–II

57

18

0.006*

 III–IV

14

16

 

Lymph-node metastasis

 pN0

54

18

0.024*

 pN+

17

16

 

Organ metastasis

 No

65

15

0.000*

 Yes

6

19

 
  1. ER estrogen receptor, FZD2 frizzled class receptor 2, Her-2 human epidermal growth factor receptor 2, PR progesterone receptor
  2. * P < .05 was considered statistically significant
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Cancer Cell International

ISSN: 1475-2867

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