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Table 1 The association between FZD2 expression and clinical-pathological characteristics in breast cancers

From: FZD2 promotes TGF-β-induced epithelial-to-mesenchymal transition in breast cancer via activating notch signaling pathway

Expression of FZD2
Factors Low (N = 71) High (N = 34) P-value
Age (years)
 ≤ 50 35 17 1
 > 50 36 17  
Tumor size (cm)
 < 2.5 31 22 0.060
 ≥ 2.5 40 12  
ER status
 (+) 35 23 0.095
 (−) 36 11  
PR status
 (+) 44 20 0.832
 (−) 27 14  
Her-2 status
 (+) 22 13 0.511
 (−) 49 21  
Ki-67 status (%)
 ≤ 20% 24 10 0.824
 > 20% 47 24  
Pathological grading
 I–II 51 23 0.655
 III 20 11  
TNM stage
 I–II 57 18 0.006*
 III–IV 14 16  
Lymph-node metastasis
 pN0 54 18 0.024*
 pN+ 17 16  
Organ metastasis
 No 65 15 0.000*
 Yes 6 19  
  1. ER estrogen receptor, FZD2 frizzled class receptor 2, Her-2 human epidermal growth factor receptor 2, PR progesterone receptor
  2. * P < .05 was considered statistically significant