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Fig. 5 | Cancer Cell International

Fig. 5

From: Silencing SHMT2 inhibits the progression of tongue squamous cell carcinoma through cell cycle regulation

Fig. 5

Knockdown of SHMT2 impaired TSCC invasive, migrative and epithelial mesenchymal transition ability. a Representative photograph of trans-well assays in HN6 and HSC3 cells after transfection with si-RNA. b, c Quantitative analysis of trans-well assays in HN6 and HSC3. d Wound healing assay images of HN6 and HSC3 cells after SHMT2 down-regulation. e, f Quantitative analysis of wound healing assay in HN6 and HSC3. g Western blot analysis images of EMT-related proteins in HN6 and HSC3 cells after SHMT2 knockdown. h, i Quantitative analysis of EMT-related proteins in HN6 and HSC3 transfected with si-RNA. P-values were obtained by Student's t-tests, * p < 0.05, ** p < 0.01, *** p < 0.001. EMT, epithelial mesenchymal transition; E-cad, E-cadherin; N-cad, N-cadherin

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Cancer Cell International

ISSN: 1475-2867

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