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Table 2 The expression percentage of CD44, CD166, and CD133 common CRC-CSCs markers in spheroids compared to their parental cells

From: Morphological and molecular characteristics of spheroid formation in HT-29 and Caco-2 colorectal cancer cell lines

Markers

Cell types

HT-29

Caco-2

Parental

Spheroid

Parental

Spheroid

CD44%

1.80 ± 0.77

19.3 ± 6.60*

1.59 ± 0.28

41.05 ± 3.53***

CD133%

1.35 ± 0.19

11.75 ± 4.69*

1.25 ± 0.45

28.25 ± 17.45*

CD166%

1.66 ± 0.37

22.40 ± 5.92*

1.78 ± 0.18

37.15 ± 4.02***

  1. Data are shown as mean ± SD of four independent experiments. A significant upregulation of CSC markers in spheroids compared to parental cells are presented as * = P < 0.05, *** = P < 0.001, ns = not significant
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Cancer Cell International

ISSN: 1475-2867

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