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Fig. 2 | Cancer Cell International

Fig. 2

From: BRD4 PROTAC degrader ARV-825 inhibits T-cell acute lymphoblastic leukemia by targeting 'Undruggable' Myc-pathway genes

Fig. 2

ARV-825 restrained the proliferation of T-ALL cell lines. a The basal BET protein level analysis in T-ALL cells, 6 T-CEM, Molt4, Jurkat and CCRF. b, c The cell growth curve of 6 T-CEM, Molt4, Jurkat and CCRF cells after treatment with DMSO or ARV-825 for 7 days. d Drug sensitivity assay of 6 T-CEM, Molt4, Jurkat and CCRF cell lines after treatment with gradient concentrations of ARV-825, JQ1, dBET1 and OTX015 for 48 h

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Cancer Cell International

ISSN: 1475-2867

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