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Table 3 Univariate Cox regression analysis of DMFS and LRRFS in the primary cohort

From: A nomogram for predicting survival of head and neck mucosal melanoma

Variable DMFS LRRFS
HR (95% CI) P HR (95% CI) P
Gender
 Male Reference   Reference  
 Female 0.964 (0.717–1.297) 0.811 1.036 (0.793–1.355) 0.794
 Age (years old)
 < 60 Reference   Reference  
 ≥ 60 1.246 (0.641–1.164) 0.134 1.070 (0.822–1.391) 0.616
Smoking
 No Reference   Reference  
 Yes 0.864 (0.625–1.236) 0.336 0.819 (0.609–1.100) 0.185
Primary site
 Others Reference   Reference  
 Nasal cavity 1.695 (1.084–2.649) 0.021* 1.795 (1.128–2.858) 0.014*
 Paranasal sinus 3.736 (2.032–6.867)  < 0.001*** 3.710 (1.995–6.897)  < 0.001***
 Oral cavity 1.9844 (1.217–3.235) 0.006** 2.631 (1.601–4.323)  < 0.001***
8th T stage
 T3 Reference   Reference  
 T4a 2.544(1.838–3.520)  < 0.001*** 1.945 (1.434–2.639)  < 0.001***
 T4b 10.314(6.861–15.502)  < 0.001*** 5.816 (4.002–8.452)  < 0.001***
8th N stage
 N0 Reference   Reference  
 N1 1.597 (1.180–2.161) 0.002** 1.665 (1.231–2.253) 0.001***
Surgery
 No Reference   Reference  
 Yes 0.758 (0.455–1.262) 0.286 0.664 (0.409–1.078) 0.098
Radiotherapy
 No Reference   Reference  
 Yes 1.359 (1.037–1.224) 0.026* 1.007 (0.771–1.316) 0.957
Chemotherapy
 No Reference   Reference  
 Yes 1.022 (0.792–1.318) 0.869 0.934 (0.718–1.215) 0.611
Immunologic/targeted therapy
 No Reference   Reference  
 Yes 0.858 (0.634–1.161) 0.320 0.801 (0.594–1.079) 0.144
  1. Cox proportional hazard model was used to conduct Cox regression analysis. * p value < 0.05; ** p value < 0.01; ** p value < 0.001