Fig. 3
From: HHLA2 predicts better survival and exhibits inhibited proliferation in epithelial ovarian cancer
Kaplan–Meier survival curves and Cox proportional hazards regression model curves of ovarian cancer patients. Kaplan–Meier survival analysis showed that a HHLA2 positive patients were correlated with slightly superior overall survival rates (Breslow’s test, p = 0.474). b platinum-resistant patients had significantly shortened survival time compared to platinum-sensitive patients. (Breslow’s test, ***p < 0.001). c Progesterone receptor (PR) negative patients tended to have shorter survival than PR positive patients. d, e Cox proportional hazards regression model demonstrated that HHLA2 expression (*p = 0.049, HR = 0.156, 95% CI = 0.025–0.992) in cancer tissue and sensitivity to platinum chemotherapy (**p = 0.002, HR = 14.14, 95% CI = 2.632–75.916) were independent prognostic factors. Platinum-resistant patients and HHLA2-negative patients had significantly inferior overall survival rates with adjusting confounding factors