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Table 3 Univariate and multivariate analysis of prognostic factors in ovarian cancer

From: HHLA2 predicts better survival and exhibits inhibited proliferation in epithelial ovarian cancer

Variable

Univariate Analysis

Multivariate Analysis

HR

P Value

95% CI

HR

P Value

95% CI

Expression of HHLA2

0.577

0.465

(0.132,2.523)

0.156

0.049

(0.025,0.992)

 Positive vs Negative

Age (years)

0.711

0.522

(0.250,2.019)

   

 < 50 vs ≥ 50

Differentiation

0.53

0.399

(0.121,2.320)

   

 Poor and moderate vs well

Pathologic type

0.439

0.275

(0.100,1.922)

   

 Serous adenocarcinoma vs other

FIGO Stage

2.568

0.211

(0.586,11.248)

   

 I and II vs III and IV

Ascites

0.275

0.211

(0.036,2.076)

   

 Positive vs Negative

Vessel

1.618

0.641

(0.213,12.262)

   

 Positive vs Negative

Lymph Node

1.763

0.376

(0.502,6.190)

   

 Positive vs Negative

Relapse

1.142

0.789

(0.433,3.011)

   

 Relapse vs No Relapse

Serum CA125 Before Surgery

22.49

0.469

(0.005,101,864.851)

   

 < 35 vs ≥ 35

Platinum Sensitivity

4.32

0.003

(1.652,11.294)

14.14

0.002

(2.632,75.916)

 Sensitive vs Resistant

CA125

1.978

0.511

(0.259,15.137)

   

 Positive vs Negative

ER

0.434

0.087

(0.167,1.128)

   

 Positive vs Negative

PR

0.328

0.028

(0.121,0.889)

   

 Positive vs Negative

  1. Bold values indicate P < 0.05
  2. ER Estrogen Receptor, PR Progesterone Receptor