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Table 3 Classification of genes enriched in the cell cycle from Reactome pathways among the 434 SRTNS

From: SNRPD1 confers diagnostic and therapeutic values on breast cancers through cell cycle regulation

M M checkpoint S S checkpoint Rest Common
AAAS NCAPG2 BUB1B NDC80 CDCA5 CCNA2 BLM PSMD3
CDCA5 NCAPH CCNB1 NUF2 CUL1 CDC45 CDC7 PSMD14
CEP152 NCAPH2 CDC20 NUP107 FEN1 MCM2 CHEK1 RPS27A
HAUS1 NDC1 CDCA8 NUP133 PCNA MCM3 GMNN  
HAUS2 NUP153 CDK1 NUP160 POLA1 MCM4 MCM10  
HAUS3 NUP155 CENPF NUP85 POLA2 MCM5 MDC1  
HAUS4 NUP205 CENPH PLK1 POLE MCM6 MND1  
HAUS5 NUP210 CENPI RCC2 PRIM1 MCM7 TOP3A  
HAUS6 NUP50 CENPO SKA1 PRIM2 ORC6 TOPBP1  
HAUS8 NUP93 CENPQ SPC24   RFC2 TPX2  
KIF20A SMC2 CENPU SPC25   RFC4 WHSC1  
MASTL SMC4 ERCC6L XPO1   RFC5   
NCAPD2 VRK1 INCENP ZW10     
NCAPD3   KIF2C ZWILCH     
NCAPG   KNTC1 ZWINT     
  1. STRING version 11.0 was used to conduct the enrichment analysis. Experimentally tested genes are highlighted in bold face. ‘M’ and ‘S’ each represents genes specific the M and S phase, respectively. ‘M checkpoint’ and ‘S checkpoint’ each means genes specific to M and S phase check point regulation, respectively, which were obtained by taking the intersection of genes between ‘M phase’ or ‘S phase’ and ‘cell cycle checkpoint’ pathways. ‘Common’ and ‘Rest’ each represents genes present in and absent from all ‘M’, ‘M checkpoint’, ‘S’, ‘S checkpoint’ categories, respectively