Fig. 4
From: Knockdown of MCM8 inhibits development and progression of bladder cancer in vitro and in vivo
Loss-of-function of MCM8 curbed bladder cancer tumorigenesis. a A nude mice model of MCM8 knockdown was constructed. b The volume of tumors was tested from feeding to sacrifice. c The fluorescence intensity was obtained through injection of D-Luciferase before sacrificing the mice. d The weight of tumors was measured after sacrificing mice. e The photograph of tumors was taken after removing tumors. f The value of Ki-67 was detected by IHC in tumor sections. Magnification times: 400 × . Results were presented as mean ± SD. *P < 0.05, **P < 0.01