Fig. 2

Transcription levels of VWCE in different types of cancer and normal tissues. a VWCE expression levels in different tumor types from the TCGA database were determined using TIMER. The color intensity (red or blue) is directly proportional to the significance level of upregulation or downregulation, respectively. VWCE mRNA expression levels in breast cancer are delineated with red highlights. P-value Significant Codes: 0 ≤ *** < 0.001 ≤ ** < 0.01 ≤ * < 0.05 ≤ . < 0.1. b The expression levels of VWCE expression in different tumor types using DriverDB. Red represents up-regulated genes with log2 (fold change) > 1 and green represents down-regulated genes with log2 (fold change) < − 1. Blue and purple dashed lines represent the average value of all tumor and normal tissues, respectively