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Fig. 5 | Cancer Cell International

Fig. 5

From: CircRNA_100290 promotes GC cell proliferation and invasion via the miR-29b-3p/ITGA11 axis and is regulated by EIF4A3

Fig. 5

Transcriptional regulation of circRNA_100290 by EIF4A3 in GC. A Prediction of circRNA_100290-related RBPs by using CircInteractome software. B RIP assay was performed to determine fold enrichment of EIF4A3 on the flanking region of circRNA_100290. C Detection of circRNA_100290 by qRT-PCR after knocking down EIF4A3 in AGS and HGC-27 cells. D Detection of EIF4A3 expression in 31 GC tissues and paired normal tissues was conducted by qRT-PCR assay. Decreased expression of EIF4A3 was observed in GC tissues. The data are presented as the mean ± SEM. ** P < 0.01. E Western blot assay was performed to determine EIF4A3 expression in 31 GC tissues and paired normal tissues. F, G Analysis of ITGA11 in predicting of OS and FP in GC patients from the Kaplan–Meier plotter website

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Cancer Cell International

ISSN: 1475-2867

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