A novel autophagy-related genes prognostic risk model and validation of autophagy-related oncogene VPS35 in breast cancer

Table 3 Association of VPS35 expression with the clinical pathological characteristics in breast cancers

Factors	Number	VPS35 expression		p value
Factors	Number	Positive	Negative	p value
Age
≤ 52	55	33	22	0.73
> 52	65	41	24
Tumor size (cm)
≤ 3	63	32	31	0.01*
> 3	57	42	15
LN metastasis
Negative	49	23	26	0.006*
Positive	71	51	20
TNM stage
I	42	22	20	0.125
II–III	78	52	26
ER status
Negative	61	43	18	0.043*
Positive	59	31	28
PR status
Negative	59	40	19	0.087
Positive	61	34	27
HER2 status
Negative	69	40	29	0.333
Positive	51	34	17
Molecular subtype
LuminalA/B	59	30	29	0.499
HER2 amplification	33	18	15
TNBC	28	18	10

ISSN: 1475-2867