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Fig. 2 | Cancer Cell International

Fig. 2

From: Circular RNA circ_0006168 enhances Taxol resistance in esophageal squamous cell carcinoma by regulating miR-194-5p/JMJD1C axis

Fig. 2

Circ_0006168 silence enhanced Taxol sensitivity of ESCC in vivo. Eca109/Taxol and KYSE150/Taxol were transfected with si-control and si-circ_0006168. A The expression of circ_0006168 was measured by qRT-PCR. B The cell viability and IC50 value of Taxol were measured by CCK-8 assay. C CCK-8 assay was employed to evaluate cell viability. D Colony formation assay was utilized to evaluate cell colony formation ability. (E, F) Transwell assay was used to determine cell migration and invasion abilities (× 100). G Cell apoptosis was examined using flow cytometry analysis. *P < 0.05, **P < 0.001, ***P < 0.0001

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