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Fig. 6 | Cancer Cell International

Fig. 6

From: circ-PTK2 (hsa_circ_0008305) regulates the pathogenic processes of ovarian cancer via miR-639 and FOXC1 regulatory cascade

Fig. 6

Circ-PTK2 performs functions in regulating cell migration, invasion, and angiogenesis. A Validation of the siRNA targeting on circ-PTK2 via reverse transcriptase-quantitative PCR (RT-qPCR) in SK-OV-3 and OVCAR-3 cells. B Validation of circ-PTK2 overexpression vector by RT-qPCR in SK-OV-3 and OVCAR-3 cells. C Transwell assay showing cell migration and invasion in SK-OV-3 cells after inhibition or overexpression of circ-PTK2. D Transwell assay showing cell migration and invasion in OVCAR-3 cells after inhibition or overexpression of circ-PTK2. E Angiogenesis was determined by Matrigel assay after inhibition of expression of circ-PTK2. Data are presented as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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