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Fig. 7 | Cancer Cell International

Fig. 7

From: circ-PTK2 (hsa_circ_0008305) regulates the pathogenic processes of ovarian cancer via miR-639 and FOXC1 regulatory cascade

Fig. 7

circ-PTK2 regulates the epithelial–mesenchymal transition (EMT) pathway. A FISH to determine the protein levels of E-cadherin and N-cadherin in SK-OV-3 cells. B FISH to determine the protein levels of E-cadherin and N-cadherin in OVCAR-3 cells. C Western blotting analysis of EMT pathway protein expression, including E-cadherin, N-cadherin, Snail, and vimentin. D Reverse transcriptase-quantitative PCR analysis of the mRNA level of E-cadherin, N-cadherin, Snail, and vimentin in SK-OV-3 and OVCAR-3 after inhibition of circ-PTK2 expression. Data are presented as the mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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