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Fig. 6 | Cancer Cell International

Fig. 6

From: The expression profiles and prognostic values of HSP70s in hepatocellular carcinoma

Fig. 6

Analysis of correlation among HSP70s, gene mutation and functional enrichment analysis of HSP70. A HSPA1A and HSPA1B, HSPA4 and HSPA8, HSPA4 and HSPA9, HSPA6 and HSPA1A, HSPA6 and HSPA1B, HSPA13 and HSPA14 had very significant correlation (correlation coefficient > 0.3). B The mutation rate of HSP70s gene was 58.55%. the mutation rates of HSPA1L, HSPA4, HSPA6 and HSPA9 are all higher than 10%, mRNA High and Amplification are the most common mutation types. Thirty neighbor genes significantly related to HSP70s were found through STRING database. Using Cytoscape 3.7.1 to display PPI results through inter-gene connectivity, we found that HSPA8 and HSPA5 played a central role in this network. Then, through the analysis, annotation, visualization and comprehensive discovery of GO (E) and KEGG (F) analysis in DAVID database

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