Skip to main content
Fig. 1 | Cancer Cell International

Fig. 1

From: Long non-coding RNA LINC01116 is activated by EGR1 and facilitates lung adenocarcinoma oncogenicity via targeting miR-744-5p/CDCA4 axis

Fig. 1

LINC01116 is markedly elevated in LAD cells and silencing LINC01116 can restrain the carcinogenic behaviors of LAD cells. A Quantification of LINC01116 expression in different cell lines was conducted via qRT-PCR. B The detection of LINC01116 knockdown efficiency was achieved by means of qRT-PCR analysis. C, D EdU and colony formation assays were employed for assessing cell proliferation capacity after LINC01116 depletion. E Apoptosis of A549 and PC9 was evaluated after LINC01116 depletion via flow cytometry. F Apoptosis-related proteins were investigated via western blot. G, H Transwell assays were utilized to evaluate the number of migrated and invaded cells was calculated after LINC01116 depletion by means of transwell assays. One-way ANOVA was applied for analysis. *P  <  0.05, **P  <  0.01

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us