Fig. 1
From: IFI35 is involved in the regulation of the radiosensitivity of colorectal cancer cells
IRF1 regulates the expression of IFI35, and their expression is positively correlated. A Luciferase reporter assay for the binding of IRF1 and IFI35 promoter and the regulation of IRF1 on IFI35. The bars show the fold of IFI35 expression relative to the empty vector. B Western blot was used to verify the expression of IFI35 after down- or upregulating IRF1. The results suggest that IRF1 modulates the expression of IFI35. C Western blot was used to verify the expression of IRF1 after down- or upregulating IFI35. The results suggest that IFI35 does not modulate the expression of IRF1. D The correlation between IRF1 and IFI35 expression was retrieved from the GEPIA database. Ad-NC: adenovirus, negative control; Ad-IRF1, adenovirus for IRF1 overexpression; sh: short hairpin RNA for the downregulation of IRF1 or IFI35. shNC: negative control short hairpin RNA