Fig. 1
Circ_0001721 was highly expressed in DXR-resistant OS tissues and cells. A qRT-PCR was used to test the expression of circ_0001721 in OS tissues (n = 51) and adjacent normal tissues (n = 51). B Expression of circ_0001721 in Chemosensitive (n = 51) and Chemoresistant (n = 51) OS tissues was detected by qRT-PCR. C KHOS, KHOS/DXR, MG63 and MG63/DXR cells were treated with different concentrations of DXR, and IC50 values were determined by CCK-8 analysis. D Circ_0001721 expression was detected in hFOB1.19 cells, parental OS cells (KHOS and MG63) and DXR-resistant OS cells (KHOS/DXR and MG63/DXR) using qRT-PCR. *P < 0.05