Table 1 CircRNAs and target miRNAs in Pathways: All circRNAs mentioned are grouped by the pathway they regulate (NF-κB, MAPK/ERK, JNK, PI3K, HIF, Wnt, VEGF) through upregulation or downregulation

MAPK

[41] hsa_circ_0003204

[42] circ-MAPK4/miR-125a-3p

[43] hsa_circ_0002124

[44] circ_LRIG3/miR-223-3p

[45] circRNA CCDC66

[46] ciRS-7/miR-7

[47] circCEP12/miR‐145‐5p

PI3K

[53] hsa_circ_0067934

[54] Hsa_circ_0002577/miR-625-5p

[55] circRHOBTB3

[56] hsa-circ-0072309/miR-100

[57] circCDK13

[58] hsa_circ_0004018

NF-κB

[60] circGLIS2/miR-671

[62] ciRS‐7/miR-7

[63] cZNF292

[64] circANKRD12

[61] circRNA-000911/miR-449a

[65] circC3P1/miR-4641

JNK

[69] circ-102004

[69] CircMAN2B2/miR‐145

[70] CircUBAP2

[71] circLPAR3/miR-198

[68] circ-ZKSCAN/miR-330-5p

Wnt

[74] circβ-catenin

[76] hsa_circ_000984

[77] circRNA_102171

[80] circ_001569

[73, 78] cir-ITCH/miR-17

[75] hsa_circ_009361/ miR-582

[78, 79] circ-ITCH/miR-214

HIF

[82] circRNF20/miR-487a

[83] circSLC25A16/miR-488-3p

[84] Circ-Erbin/miR-125a-5p

[84] Circ-Erbin/miR-138-5p

[85] circDENND2A/miR-625-5p

[86] hsa-circ-0046600/miR-640

[87] circRNA_100859/miR-217

[89] circDENND4C

[90] circ-0000977/miR-153

[91] circ-PIP5K1A/miR-600

[93] circ-HIPK3/miR-338-3p

[88] circFAM120A

[92] circ-CDR1as/miR-135b-5p

VEGF

[97] circ_001621/miR-578

[98] circMYLK/miR-29a

[99] circPVT1

[100] hsa_circ_0000096

[101] circPRRC2A/miR-514a-5p

[101] circPRRC2A/ miR-6776-5p