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Fig. 6 | Cancer Cell International

Fig. 6

From: Downregulation of Tim-1 inhibits the proliferation, migration and invasion of glioblastoma cells via the miR-133a/TGFBR1 axis and the restriction of Wnt/β-catenin pathway

Fig. 6

Upregulated miR-133a inhibited the proliferation, invasion and migration of glioblastoma cells, which could be reversed by upregulated TGFBR1. TGFBR1 expression in U87 and U251 cells was detected using qRT-PCR (A) and WB (B); C The proliferation ability of U87 and U251 cells was detected by CCK-8 detection; D The invasion ability of U87 and U251 cells was detected by Transwell assay; E The migration ability of U87 and U251 cells was detected by wound healing test. *represented comparison with mimic NC, p < 0.05; + represented comparison with miR-133a mimic + pcDNA3.1, p < 0.05. n = 3. Data were expressed as mean ± standard deviation. One-way ANOVA was used for comparisons between multiple groups, comparison between two groups are followed by t test with Bonferroni correction

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Cancer Cell International

ISSN: 1475-2867

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