Fig. 2

A Venn plot of differentially expressed genes among 5 series. B Volcano plot to visualize the gene distribution. Red dots represented up-regulated DEGs, green dots represented down-regulated DEGs and black dots represented normal genes. C Bubble chart of functional and pathway enrichment analysis of up-regulated genes. D Bubble chart of functional and pathway enrichment analysis of down-regulated genes. E Gene set enrichment analysis of the whole DEGs