Fig. 4

OIP5-AS1 contributes to the growth of EC cells via down-regulating miR-152-3p expression. A MiR-152-3p down-regulation efficiency examined in Ishikawa and ECC cells. B EC cells were treated with sh-NC, sh-OIP5-AS1#1, sh-OIP5-AS1#1 + NC inhibitor, sh-OIP5-AS1#1 + miR-152-3p inhibitor and colony formation assays evaluated the proliferation of transfected cells. C Flow cytometry analysis assessed cell apoptosis rate in transfected cells. D Western blot evaluated apoptosis-related proteins in transfected cells. E, F Transwell assays tested migratory and invasive abilities of transfected cells. G Western blot measured proteins of EMT of transfected cells. **P < 0.01