Fig. 2
From: Elevated exosome-derived miRNAs predict osimertinib resistance in non-small cell lung cancer
Cluster analysis of miRNAs and target genes. A Volcano map of differentially expressed miRNAs. Each point in the volcano map represents a gene, and the red dots are significantly different genes that satisfy both [logFC] > 1 and FDR < 0.05 thresholds. The blue dots are genes that only meet FDR < 0.05, and the green dots are genes that only meet [logFC] > 1. B H1975-OR top 10 up-regulated miRNAs (red) and top 10 down-regulated miRNAs (green) compared with H1975. C KEGG pathway enrichment analysis of target genes for differentially expressed miRNA (histogram). The ordinate represents the name of the pathway, and the abscissa is the number of genes involved in each pathway. D Calculate the Pearson coefficient of cell supernatant and patient serum.. The correlation coefficient uses Pearson’s correlation test (column, row), and the color of each square corresponds to the correlation coefficient value