Skip to main content

Table 1 The differentially expressed proteins between EBV-positive and negative GC

From: Identification of differential proteomics in Epstein-Barr virus-associated gastric cancer and related functional analysis

Genes

Protein description

FC (abs)

P value

Regulation

GBP5

Guanylate-binding protein 5

3.45

0.028

Up

C5AR1

C5a anaphylatoxin chemotactic receptor 1

3.39

0.038

Up

THRAP3

Thyroid hormone receptor-associated protein 3

3.25

0.002

Up

P3H3

Prolyl 3-hydroxylase 3

3.10

0.035

Up

MDK

Midkine

3.07

0.042

Up

ALOX5AP

Arachidonate 5-lipoxygenase-activating protein

2.84

0.048

Up

BPI

Bactericidal permeability-increasing protein

2.69

0.025

Up

HLA-DRB1

HLA class II histocompatibility antigen, DRB1-12 beta chain

2.56

0.015

Up

PPL

Periplakin

2.49

0.027

Up

ISLR

Immunoglobulin superfamily containing leucine-rich repeat protein

2.31

0.047

Up

APOL2

Apolipoprotein L2

2.29

0.009

Up

HCK

Tyrosine-protein kinase HCK

2.21

0.020

Up

AKAP2

A-kinase anchor protein 2

2.17

0.026

Up

ITGA11

Integrin alpha-11

2.14

0.024

Up

ITGB2

Integrin beta-2

2.13

0.025

Up

COQ6

Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial

2.09

0.039

Up

DENND1C

DENN domain-containing protein 1C

2.06

0.002

Up

RAB31

Ras-related protein Rab-31

2.05

0.041

Up

CYBA

Cytochrome b-245 light chain

2.02

0.001

Up

FCGR3A

Low affinity immunoglobulin gamma Fc region receptor III-A

1.94

0.044

Up

CYBB

Cytochrome b-245 heavy chain

1.90

0.007

Up

KEAP1

Kelch-like ECH-associated protein 1

1.88

0.003

Up

KALRN

Kalirin

1.86

 < 0.001

Up

GBP1

Guanylate-binding protein 1

1.85

0.020

Up

DPYD

Dihydropyrimidine dehydrogenase [NADP( +)]

1.81

0.049

Up

TOR1B

Torsin-1B

1.80

0.014

Up

CNN2

Calponin-2

1.78

0.041

Up

TCIRG1

V-type proton ATPase 116 kDa subunit a isoform 3

1.78

0.023

Up

TAP1

Antigen peptide transporter 1

1.76

0.037

Up

SRRM2

Serine/arginine repetitive matrix protein 2

1.75

0.026

Up

CD40

Tumor necrosis factor receptor superfamily member 5

1.74

0.036

Up

FUT8

Alpha-(1,6)-fucosyltransferase

1.71

0.037

Up

SCAF1

Splicing factor, arginine/serine-rich 19

1.69

0.044

Up

TLR3

Toll-like receptor 3

1.66

0.020

Up

GRN

Granulins

1.65

0.029

Up

NSA2

Ribosome biogenesis protein NSA2 homolog

1.64

0.050

Up

CLASP1

CLIP-associating protein 1

1.61

0.033

Up

CPOX

Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

1.61

0.023

Up

ATP6AP1

V-type proton ATPase subunit S1

1.60

0.022

Up

CARHSP1

Calcium-regulated heat-stable protein 1

1.60

0.037

Up

LPCAT2

Lysophosphatidylcholine acyltransferase 2

1.59

0.040

Up

GALNT2

Polypeptide N-acetylgalactosaminyltransferase 2

1.59

0.038

Up

COMMD10

COMM domain-containing protein 10

1.59

0.032

Up

ATP6V1D

V-type proton ATPase subunit D

1.57

0.020

Up

LRRC40

Leucine-rich repeat-containing protein 40

1.54

0.011

Up

PREX1

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

1.53

0.029

Up

GBP2

Guanylate-binding protein 2

1.53

0.023

Up

PEBP1

Phosphatidylethanolamine-binding protein 1

1.51

0.016

Down

UBR5

E3 ubiquitin-protein ligase UBR5

1.51

0.049

Down

TXN2

Thioredoxin, mitochondrial

1.52

0.011

Down

ADD1

Alpha-adducin

1.52

0.019

Down

EPB41L1

Band 4.1-like protein 1

1.52

0.033

Down

IDI1

Isopentenyl-diphosphate Delta-isomerase 1

1.54

0.009

Down

EML2

Echinoderm microtubule-associated protein-like 2

1.55

0.035

Down

ATP1B1

Sodium/potassium-transporting ATPase subunit beta-1

1.55

0.035

Down

EIF4A2

Eukaryotic initiation factor 4A-II

1.56

0.004

Down

MRI1

Methylthioribose-1-phosphate isomerase

1.56

0.009

Down

CST3

Cystatin-C

1.56

0.035

Down

ABHD14B

Protein ABHD14B

1.57

0.013

Down

ARFIP2

Arfaptin-2

1.58

0.021

Down

ATPAF2

ATP synthase mitochondrial F1 complex assembly factor 2

1.58

0.014

Down

PSMG4

Proteasome assembly chaperone 4

1.59

0.036

Down

ECSIT

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1.59

0.030

Down

RNMT

mRNA cap guanine-N7 methyltransferase

1.59

0.019

Down

CD46

Membrane cofactor protein

1.61

0.022

Down

SUPV3L1

ATP-dependent RNA helicase SUPV3L1, mitochondrial

1.61

0.042

Down

DTD1

D-aminoacyl-tRNA deacylase 1

1.61

0.009

Down

FAM213A

Redox-regulatory protein FAM213A

1.63

0.019

Down

C11orf54

Ester hydrolase C11orf54

1.63

0.049

Down

BCKDHB

2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

1.64

0.012

Down

GFPT1

Glutamine–fructose-6-phosphate aminotransferase [isomerizing] 1

1.64

0.043

Down

EPB41L2

Band 4.1-like protein 2

1.64

0.035

Down

RAB6D/RAB6C

Ras-related protein Rab-6D/Ras-related protein Rab-6C

1.66

0.025

Down

DAG1

Dystroglycan

1.66

0.018

Down

HEBP2

Heme-binding protein 2

1.67

0.039

Down

QDPR

Dihydropteridine reductase

1.68

0.047

Down

UBE4B

Ubiquitin conjugation factor E4 B

1.68

0.045

Down

NAXE

NAD(P)H-hydrate epimerase

1.68

0.007

Down

GLRX5

Glutaredoxin-related protein 5, mitochondrial

1.70

0.006

Down

PPOX

Protoporphyrinogen oxidase

1.70

0.012

Down

CHRAC1

Chromatin accessibility complex protein 1

1.71

0.048

Down

MPST

3-mercaptopyruvate sulfurtransferase

1.73

0.015

Down

COQ3

Ubiquinone biosynthesis O-methyltransferase, mitochondrial

1.73

0.015

Down

F13A1

Coagulation factor XIII A chain

1.74

0.033

Down

SGCD

Delta-sarcoglycan

1.75

0.020

Down

NFU1

NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

1.75

0.016

Down

TXLNG

Gamma-taxilin

1.76

0.010

Down

NRM

Nurim

1.78

0.026

Down

ACAA2

3-ketoacyl-CoA thiolase, mitochondrial

1.78

0.015

Down

TXNL4A

Thioredoxin-like protein 4A

1.80

0.024

Down

F11R

Junctional adhesion molecule A

1.80

0.009

Down

H2AFY2

Core histone macro-H2A.2

1.81

0.020

Down

SPRYD4

SPRY domain-containing protein 4

1.82

0.049

Down

RIDA

2-iminobutanoate/2-iminopropanoate deaminase

1.83

0.012

Down

MLYCD

Malonyl-CoA decarboxylase, mitochondrial

1.85

0.007

Down

ACY1

Aminoacylase-1

1.87

0.001

Down

CDC5L

Cell division cycle 5-like protein

1.88

0.018

Down

ACSS2

Acetyl-coenzyme A synthetase, cytoplasmic

1.89

0.014

Down

DARS2

Aspartate–tRNA ligase, mitochondrial

1.94

0.014

Down

2-Mar

Mitochondrial amidoxime reducing component 2

1.96

0.008

Down

CA1

Carbonic anhydrase 1

1.99

0.025

Down

BRK1

Protein BRICK1

2.00

0.005

Down

CAVIN2

Caveolae-associated protein 2

2.02

0.029

Down

SELENBP1

Methanethiol oxidase

2.03

0.037

Down

COQ8A

Atypical kinase COQ8A, mitochondrial

2.04

0.030

Down

HBG1

Hemoglobin subunit gamma-1

2.07

0.021

Down

PFN2

Profilin-2

2.07

 < 0.001

Down

ARHGEF10

Rho guanine nucleotide exchange factor 10

2.08

0.003

Down

GRIP2

Glutamate receptor-interacting protein 2

2.12

0.023

Down

SH3BGRL2

SH3 domain-binding glutamic acid-rich-like protein 2

2.14

0.034

Down

TMEM63A

CSC1-like protein 1

2.18

0.048

Down

CRAT

Carnitine O-acetyltransferase

2.18

0.003

Down

HBE1

Hemoglobin subunit epsilon

2.26

0.036

Down

IGKV2-24

Immunoglobulin kappa variable 2–24

2.28

0.023

Down

VWA5A

von Willebrand factor A domain-containing protein 5A

2.36

0.012

Down

MAOB

Amine oxidase [flavin-containing] B

2.37

0.009

Down

DEPTOR

DEP domain-containing mTOR-interacting protein

2.39

0.013

Down

LTBP4

Latent-transforming growth factor beta-binding protein 4

2.40

0.029

Down

THADA

Thyroid adenoma-associated protein

2.45

0.049

Down

ACSS1

Acetyl-coenzyme A synthetase 2-like, mitochondrial

2.45

0.023

Down

ASS1

Argininosuccinate synthase

2.47

0.013

Down

EPHB3

Ephrin type-B receptor 3

2.54

0.015

Down

ADH1B

Alcohol dehydrogenase 1B

2.64

0.044

Down

HMGCS1

Hydroxymethylglutaryl-CoA synthase, cytoplasmic

2.65

0.046

Down

SLC12A2

Solute carrier family 12 member 2

2.72

0.002

Down

PTGR1

Prostaglandin reductase 1

2.73

0.002

Down

PHGDH

D-3-phosphoglycerate dehydrogenase

2.75

0.005

Down

LRRC1

Leucine-rich repeat-containing protein 1

2.75

0.011

Down

FAF1

FAS-associated factor 1

2.86

0.018

Down

OPLAH

5-oxoprolinase

2.87

0.003

Down

CKMT1A

Creatine kinase U-type, mitochondrial

2.91

0.048

Down

CEP250

Centrosome-associated protein CEP250

3.19

0.004

Down

BCAM

Basal cell adhesion molecule

3.55

0.029

Down

EPHB2

Ephrin type-B receptor 2

3.80

0.047

Down

MFAP4

Microfibril-associated glycoprotein 4

4.09

0.034

Down

AKR7A3

Aflatoxin B1 aldehyde reductase member 3

4.11

0.034

Down

TMEM168

Transmembrane protein 168

4.56

0.011

Down

  1. EBV Epstein-Barr virus, GC gastric cancer, FC (abs) absolute fold change
Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us