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Fig. 8 | Cancer Cell International

Fig. 8

From: WD40 repeat 43 mediates cell survival, proliferation, migration and invasion via vimentin in colorectal cancer

Fig. 8

VIM overexpression partially restores the proliferative and migratory ability of CRC cells following WDR43 knockdown. a The expression of WDR43 and VIM in each group were detected by western blotting. Cell proliferation was detected by b MTT and c Celigo assays in DLD-1 cells (statistically significant differences of proliferation between KD + NC and NC + NC, KD + OE and KD + NC, OE + NC and KD + OE in two assays were found in day 4 and day 5, p < 0.05). d Transwell migration assay was also performed in DLD-1 cells (statistically significant differences of migration between KD + NC and NC + NC, KD + OE and KD + NC, OE + NC and KD + OE in two assays were found, p < 0.05). VIM vimentin, CRC colorectal cancer, WDR WD40 repeat, NC negative control, KD WDR43 knockdown, OE VIM overexpression

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Cancer Cell International

ISSN: 1475-2867

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