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Table 2 The frequency distribution and logistic regression analysis of the polymorphism of WISP1 gene in gastric cancer and control group

From: Association between WNT-1-inducible signaling pathway protein-1 (WISP1) genetic polymorphisms and the risk of gastric cancer in Guangxi Chinese

Variables

Gastric cancer (N = 204) n (%)

Controls (N = 227) n (%)

AOR (95% CI)

P

rs2929973

 Alleles

  T

285 (69.9)

295 (65.0)

1.00ref

 

  G

123 (30.1)

159 (35.0)

0.83 (0.61–1.13)

0.230

 Co-dominant

  TT

100 (49.0)

102 (44.9)

1.00ref

 

  TG

85 (41.7)

91 (40.1)

0.99 (0.64–1.54)

0.967

  GG

19 (9.3)

34 (15.0)

0.63 (0.32–1.21)

0.164

 Dominant

  TT

100 (49.0)

102 (44.9)

1.00ref

 

  TG + GG

104 (51.0)

125 (55.1)

0.88 (0.58–1.32)

0.536

 Recessive

  TT + TG

185 (90.7)

193 (85.0)

1.00ref

 

  GG

19 (9.3)

34 (15.0)

0.62 (0.33–1.17)

0.141

 rs7843546

 Allele

  C

191 (46.8)

191 (42.1)

1.00ref

 

  T

217 (53.2)

263 (57.9)

0.84 (0.63–1.12)

0.224

 Co-dominant

  CC

41 (20.1)

36 (15.9)

1.00ref

 

  CT

109 (53.4)

119 (52.4)

0.86 (0.49–1.48)

0.577

  TT

54 (26.5)

72 (31.7)

0.68 (0.37–1.24)

0.204

 Dominant

  CC

41 (20.1)

36 (15.9)

1.00ref

 

  CT + TT

163 (79.9)

191 (84.1)

0.79 (0.47–1.33)

0.376

 Recessive

  CT + CC

150 (73.5)

155 (68.3)

1.00ref

 

  TT

54 (26.5)

72 (31.7)

0.78 (0.50–1.21)

0.262

rs10956697

 Allele

  C

278 (68.1)

286 (63.0)

1.00ref

 

  A

130 (31.9)

168 (37.0)

0.88 (0.65–1.20)

0.421

 Co-dominant

  CC

95 (46.6)

86 (37.9)

1.00ref

 

  AC

88 (43.1)

114 (50.2)

0.78 (0.50–1.19)

0.248

  AA

21 (10.3)

27 (11.9)

0.90 (0.45–1.79)

0.771

 Dominant

  CC

95 (46.6)

86 (37.9)

1.00ref

 

  AC + AA

109 (53.4)

141 (62.1)

0.79 (0.52–1.19)

0.254

 Recessive

  CC + AC

183 (89.7)

200 (88.1)

1.00ref

 

  AA

21 (10.3)

27 (11.9)

1.02 (0.53–1.96)

0.947

  1. ref reference; AOR Adjusted odds ratio; 95% CI 95% confidence interval; adjusted for age, BMI ethnicity, smoking and drinking alcohol