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Table 5 Distribution frequency of WISP1polymorphisms in controls and gastric cancer patients stratified by cell differentiation

From: Association between WNT-1-inducible signaling pathway protein-1 (WISP1) genetic polymorphisms and the risk of gastric cancer in Guangxi Chinese

Variables Moderate and poor differentiation Well differentiation
Controls (N = 227) Cancer (N = 168) AOR (95% CI) P Cancer (N = 36) AOR (95% CI) P
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 Co-dominant TT 102(44.9) 81(48.2) 1.00ref   19(52.8) 1.00ref  
 TG 91(40.1) 72(42.9) 1.03(0.65–1.62) 0.912 13(36.1) 0.86(0.36–2.07) 0.730
 GG 34(15.0) 15(8.9) 0.60(0.29–1.21) 0.151 4(11.1) 0.96(0.27–3.39) 0.953
 Dominant TT 102(44.9) 81(48.2) 1.00ref   19(52.8) 1.00ref  
 TG + GG 125(55.1) 87(51.8) 0.90(0.58–1.37) 0.612 17(47.2) 0.88(0.39–1.99) 0.766
 Recessive TT + TG 193(85.0) 153(91.1) 1.00ref   32(88.9) 1.00ref  
 GG 34(15.0) 15(8.9) 0.59(0.30–1.14) 0.117 4(11.1) 1.03(0.31–3.42) 0.960
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 Co-dominant CC 36(15.9) 34(20.2) 1.00ref   7(19.4) 1.00ref  
 CT 119(52.4) 86(51.2) 0.79(0.45–1.41) 0.426 23(63.9) 1.14(0.40–3.24) 0.801
 TT 72(31.7) 48(28.6) 0.71(0.38–1.31) 0.272 6(16.7) 0.42(0.11–1.56) 0.197
 Dominant CC 36(15.9) 34(20.2) 1.00ref   7(19.4) 1.00ref  
 CT + TT 191(84.1) 134(79.8) 0.77(0.45–1.32) 0.333 29(80.6) 0.87(0.31–2.39) 0.782
 Recessive CT + CC 155(68.3) 120(71.4) 1.00ref   30(83.3) 1.00ref  
 TT 72(31.7) 48(28.6) 0.86(0.54–1.35) 0.504 6(16.7) 0.38(0.14–1.07) 0.067
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 Co-dominant CC 86(37.9) 79(47.0) 1.00ref   16(44.4) 1.00ref  
 AC 114(50.2) 70(41.7) 0.73(0.46–1.14) 0.165 18(50.0) 0.90(0.39–2.04) 0.792
 AA 27(11.9) 19(11.3) 0.96(0.47–1.93) 0.902 2(5.6) 0.67(0.13–3.55) 0.636
 Dominant CC 86(37.9) 79(47.0) 1.00ref   16(44.4) 1.00ref  
 AC + AA 141(62.1) 89(53.0) 0.76(0.49–1.16) 0.201 20(55.6) 0.86(0.39–1.93) 0.719
 Recessive CC + AC 200(88.1) 149(88.7) 1.00ref   34(94.4) 1.00ref  
 AA 27(11.9) 19(11.3) 1.12(0.58–2.17) 0.739 2(5.6) 0.71(0.14–3.55) 0.677
  1. ref reference; AOR Adjusted odds ratio; 95% CI 95% confidence interval; adjusted for gender, age, BMI, ethnicity, smoking and drinking alcohol