Fig. 3From: Role of glutamine and its metabolite ammonia in crosstalk of cancer-associated fibroblasts and cancer cellsOncogenic regulation of GLN metabolism. Driven by oncogenes and ammonia concentration, CAFs can secrete nutrients such as Glu and cytokines, thus promoting the metabolic changes of tumor cells and the growth and development of cancer cells. The red pointed arrow heads indicate activation interactions. The black pointed arrow heads indicate material transportation. The blue blunt arrowheads indicate inhibitory interactionsBack to article page