Fig. 2

NAT10 is a key risk gene and independent prognostic factor of HNSCC in TCGA and GEO datasets. a, b NAT10, identified from TCGA and GEO data, was the most significant contributor to the hazard ratio of the model (RBM15B was not found in the GEO dataset). c In the TCGA cohort, the mRNA expression of NAT10 in tumour tissues was higher than that in normal tissues. d High expression of NAT10 was a poor prognostic factor for HNSCC (log-rank test, P = 0.001). e HNSCC samples were divided into NAT10-high and NAT10-low expression groups according to the median expression of NAT10. GSEA was performed, and the pathways associated with high NAT10 expression are shown