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Table 3 Summary of the subgroup analyses of the association between OS and clinicopathological features in PC

From: The impact of LncRNA dysregulation on clinicopathology and survival of pancreatic cancer: a systematic review and meta-analysis (PRISMA compliant)

Multivariate analysis Univariate analysis
  Included studies HR (95% CI) P value I2 (%) Effect model Included studies HR (95% CI) P value I2 (%) Effect model
Gender 23 0.01 (− 0.14, 0.17) 0.868 0.0% Fixed 10 0.04 (− 0.07, 0.16) 0.344 8.5% Fixed
Distance metastasis 20 0.08 (0.02, 0.13) 0.000 74.7% Random 1 0.02 (− 0.53, 0.57) 0.000 0%
Node metastasis 29 0.20 (0.12, 0.28) 0.000 65.9% Random 5 − 0.12 (− 0.34, 0.11) 0.000 83.0% Random
Differentiation 20 0.34 (0.22, 0.46) 0.145 25.4% Fixed 12 0.15 (0.01, 0.29) 0.921 0% Fixed
Neural and prineural invasion 13 0.24 (0.11, 0.36) 0.002 61.1% Random 11 0.01 (− 0.01, 0.02) 0.178 28.0% Fixed
Vascular invasion 9 0.36 (0.17, 0.56) 0.047 50.9% Random 2 0.24 (− 0.14, 0.62) 0.339 0.0% Fixed
TNM 30 0.07 (− 0.15, 0.29) 0.000 76.4% Random
Stage 15 0.10 (− 0.00, 0.19) 0.000 69.8% Random 4 0.48 (0.26, 0.70) 0.004 77.9% Random
  1. HR hazard ratio, 95% CI confidence intervals