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Table 3 The co-expression analysis was performed between LYRM4 and the proteins involved in mitochondrial Fe/S protein assembly and export at transcript levels in LIHC using GEPIA2 web

From: Iron-sulphur cluster biogenesis factor LYRM4 is a novel prognostic biomarker associated with immune infiltrates in hepatocellular carcinoma

Gene A Gene B LIHC tumor LIHC normal Liver
p-value R p-value R p-value R
LYRM4 ISCU 0.011 0.13 9e–08 0.67 0 0.71
NFU1 0 0.45 3.5e–08 0.69 0 0.78
BOLA1 2.1e–11 0.26 0.00098 0.45 2.8e–06 0.43
BOLA3 0.00024 0.19 0.29 0.15 4.4e–16 0.68
NFS1 0.022 0.12 0.32 – 0.14 0.08 0.17
ACP1 3.5e–09 0.3 0.042 0.29 0 0.7
ISCA1 0.063 0.097 0.015 0.34 0 0.72
ISCA2 4.7e–08 0.28 2.4e–05 0.56 2.2e–16 0.68
IBA57 0.32 0.052 0.34 0.14 0.0011 0.31
FXN 0.024 0.12 0.19 0.19 0.023 0.22
FDX1L 2.1e–11 0.34 6.3e–07 0.64 2.1e–14 0.65
FDXR 0.73 0.018 0.0079 0.37 0.0014 0.3
HSC20 6.4e–06 0.23 0.016 0.34 8.2e–10 0.54
HSPA9 0.36 – 0.047 0.3 0.15 4.8e–10 0.55
GLRX5 0.66 –0.023 0.00061 0.47 2.7e–06 0.43
ABCB7 0.22 0.064 0.025 0.32 1.1e–09 0.54
NUBPL 0.13 0.079 0.48 0.1 0.14 0.14
MFRN1 0.81 0.012 0.027 0.31 0.00035 0.33
MFRN2 0.48 – 0.037 0.73 0.05 0.31 0.098
POLD1a 4.4e–16 0.41 3.6e–07 0.65 0 0.74
PRIM2a 0 0.5 0.014 0.35 0 0.74
  1. The bold values indicate the significant difference between the two groups of data, and the statistical significance was set at p < 0.05
  2. aRepresents the key iron-sulphur proteins outside the mitochondria