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Fig. 4 | Cancer Cell International

Fig. 4

From: Study of cellular heterogeneity and differential dynamics of autophagy in human embryonic kidney development by single-cell RNA sequencing

Fig. 4

Heterogenetic interstitial cells present complex gene expression pattern. a UMAP plot of IPCs and ICs subgroups, IC1–IC2. b The pseudotime trajectory plot of IPCs and ICs subgroups. The pseudotime showed the differentiation start to the end. c The violin plot presents marker genes of IPCs and ICs subgroups. d DEGs of IC1 and IC2: red dots represent upregulated genes in IC1; blue dots represent down-regulated genes in IC1. e Different ATG expression of NPCs subgroups. ** represented P value < 0.01; *** represented P value < 0.001. f Top 10 enriched TFs in IPCs and ICs subgroups. g GSVA results of IPCs and ICs subgroups. Red represent upregulated pathways; blue represent down-regulated pathways

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Cancer Cell International

ISSN: 1475-2867

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