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Fig. 3 | Cancer Cell International

Fig. 3

From: Circ-SFMBT2 drives the malignant phenotypes of esophageal cancer by the miR-107-dependent regulation of SLC1A5

Fig. 3

Circ-SFMBT2 was identified as a miR-107 sponge. A Starbase predicted the binding sites between miR-107 and circ-SFMBT2. B The transfection efficiency of miR-107 was analyzed by qRT-PCR. C–H) Dual-luciferase reporter assay (C, D), RIP assay (E, F) and RNA pull-down assay (G, H) were performed to validate the interaction between miR-107 and circ-SFMBT2. I The qRT-PCR was performed to examine the miR-107 expression in normal and EC tissues. J Pearson’s correlation coefficient was conducted to analyze the linear relation between circ-SFMBT2 and miR-107. K The miR-107 level was detected by qRT-PCR in HEEC, KYSE150 and TE1 cells. L The overexpression efficiency of circ-SFMBT2 was evaluated using qRT-PCR. M The effect of circ-SFMBT2 on the expression of miR-107 was measured using qRT-PCR. ***P < 0.001, ****P < 0.0001

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Cancer Cell International

ISSN: 1475-2867

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