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Fig. 6 | Cancer Cell International

Fig. 6

From: USP39 promotes malignant proliferation and angiogenesis of renal cell carcinoma by inhibiting VEGF-A165b alternative splicing via regulating SRSF1 and SRPK1

Fig. 6

The expression level of USP39 affects the interaction between SRPK1 and SRSF1 and the effect of USP39 expression on VEGF-A variable splicing. A USP39 overexpression promoted the interaction between SRPK1 and SRSF1. B USP39 knockdown inhibited the interaction between SRPK1 and SRSF1. C USP39 overexpression promoted SRPK1 and SRPK1, and phosphorylation of SRSF1. D USP39 knockdown inhibited SRPK1 phosphorylation of SRSF1. E Total VEGF and VEGF-165b expression after USP39 knockdown or overexpression. The densitometry quantification of the western blots under each blot

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Cancer Cell International

ISSN: 1475-2867

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