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Fig. 1 | Cancer Cell International

Fig. 1

From: The plasma exosomal miR-1180-3p serves as a novel potential diagnostic marker for cutaneous melanoma

Fig. 1

Characterization of circulating exosomes in melanoma. A Distribution of mappable small RNAs by small RNA sequencing in exosomes from plasma of melanoma patients (MM, n = 20) and healthy donors (NO, n = 20). Small RNA sequencing was performed as described in Methods. B Volcano plot of the differentially expressed exosomal miRNAs between two groups. Significantly downregulated genes are in blue (sig = True), and significantly up-regulated genes are in red (sig = True). Non-significant genes are in black (sig = False). Black vertical lines highlight log fold changes of − 1 and 1, while Black horizontal line represents a padj of 0.001

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