Fig. 1

Xanthine dehydrogenase (XDH) expression levels in different types of human cancers. A A snapshot of XDH mRNA expression levels in 20 different types of cancers based on the Oncomine database. The datasets displayed in the colored rectangles are those with statistically significant XDH mRNA overexpression (right) and underexpression (left) in cancer tissue versus normal tissue. The threshold was set as follows: p-value of 0.001, fold change of 1.5, and gene ranking of all. B Human XDH expression levels in different tumor types from The Cancer Genome Atlas (TCGA) database were determined by the TIMER database (*p < 0.05, **p < 0.01, ***p < 0.001)