Fig. 5From: LINC00665 up-regulates SIN3A expression to modulate the progression of colorectal cancer via sponging miR-138-5pLINC00665 accelerated proliferation, migration and invasion of CRC cells and impeded cell apoptosis by up-regulating SIN3A. A EdU experiments were performed to estimate cell proliferation in response to transfection with indicated plasmids including sh-NC, sh-LINC00665#1, and sh-LINC00665#1 + pcDNA3.1-SIN3A (×100 magnification). B, C Cell apoptosis was evaluated by JC-1 (×200 magnification) and flow cytometry experiments under different transfection conditions. D, E Transwell assays were implemented to detect cell migration and invasion in different groups (×100 magnification). **P < 0.01Back to article page