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Table 2 CircRNAs with oncogenic functions in RCC

From: Circular RNAs and their role in renal cell carcinoma: a current perspective

CircRNA Target miRNA/gene axis Gene/Protein activity Functions in RCC Ref
circPCNXL2 miR-153/ZEB2 Increased Increased proliferation and invasion [73]
circ0039569 miR-34a-5p/CCL22 Increased Increased proliferation, migration and invasion [72]
circZNF609 miR-138-5p/FOXP4 Increased Increased proliferation and invasion [75]
circFNDC3B miR-99a/JAK1/STAT3/MEK/ERK Increased Increased proliferation and migration [76]
circNRIP1 miR-505/AMPK/PI3K/AKT/mTOR Increased Increased proliferation and migration [77]
circ001895 miR-296-5p/SOX12 Increased Increased proliferation, migration, invasion and decreased apoptosis [78]
circEGLN3 miR-1299/IRF7 Increased Increased proliferation, migration, invasion and decreased apoptosis [79]
circABCB10 Increased proliferation and migration
decreased apoptosis
[80]
circ000926 miR-411/CDH2 Increased Increased proliferation, migration, invasion and EMT [85]
circPRRC2A miR-514a-5p
miR-6776-5p/TRPM3
Increased Increased proliferation and EMT [69]
circ0035483 miR-335/CCNB1 Increased Increased proliferation, autophagy and resistance to Gemcitabine [70]