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Fig. 2 | Cancer Cell International

Fig. 2

From: Calculated identification of mutator-derived lncRNA signatures of genomic instability to predict the clinical outcome of muscle-invasive bladder cancer

Fig. 2

Identification and functional annotation of GIlncRNAs in MIBC patients. a Based on the expression patterns of 43 genomic instability-related lncRNAs, unsupervised clustering of 399 MIBC patients. The blue cluster on the left is GS-like group, and the red cluster on the right is GU-like group. b Boxplots of somatic mutations in the GS-like group and GU-like group. The accumulation of somatic mutations in the GS-like group is significantly lower than that in the GU-like group. c Boxplots of the expression level of UBQLN4 in the GU-like group and GS-like group. The expression level of UBQLN4 in GS-like group was significantly lower than that in GU-like group. d Co-expression network of differential lncRNA related to genomic instability and their corresponding mRNAs. The blue circles represent lncRNAs, and the red circles represent mRNAs. e KEGG pathway analysis the main signalling pathways for mRNAs related to differential lncRNAs

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Cancer Cell International

ISSN: 1475-2867

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