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Table 1 Clinical characteristics of TCL patients

From: TNFAIP3 mutation may be associated with favorable overall survival for patients with T-cell lymphoma

Variables JNU dataset GDPH dataset COSMIC dataset GSE15842 dataset
Number 41 79 544 47
Gender, n (%)
 Female 19 (46.3) 30 (38.0)
 Male 22 (53.7) 49 (62.0)
Age, y, mean ± SD 48 ± 19 46 ± 19
Subtype, n (%)a
 AITL 5 (12.2) 18 (22.8) 101 (18.6) 0 (0.0)
 ALCL 1 (2.4) 6 (7.6) 19 (3.5) 0 (0.0)
 ATLL 0 (0.0) 0 (0.0) 292 (53.7) 0 (0.0)
 CTCL 1 (2.4) 1 (1.3) 73 (13.4) 0 (0.0)
 EATL 1 (2.4) 0 (0.0) 0 (0.0) 0 (0.0)
 HSTCL 0 (0.0) 1 (1.3) 3 (0.6) 0 (0.0)
 MEITL 0 (0.0) 1 (1.3) 0 (0.0) 0 (0.0)
 NKTCL 15 (36.6) 15 (19.0) 7 (1.3) 0 (0.0)
 PTCL-NOS 5 (12.2) 18 (22.8) 48 (8.8) 47 (100%)
 SPTCL 1 (2.4) 1 (1.3) 0 (0.0) 0 (0.0)
 T-LBL 9 (22.0) 18 (22.8) 0 (0.0) 0 (0.0)
 T-LGLL 3 (7.3) 0 (0.0) 1 (0.2) 0 (0.0)
Country, n (%)a
 China 41 (100) 79 (100) 0 (0.0) 0 (0.0)
 USA 0 (0.0) 0 (0.0) 237 (43.6) 0 (0.0)
 Japan 0 (0.0) 0 (0.0) 291 (53.5) 0 (0.0)
 Australia 0 (0.0) 0 (0.0) 9 (1.7) 0 (0.0)
 Italy 0 (0.0) 0 (0.0) 5 (0.9) 0 (0.0)
 Germany 0 (0.0) 0 (0.0) 0 (0.0) 47 (100%)
 Unknown 0 (0.0) 0 (0.0) 4 (0.7) 0 (0.0)
Detection method PCR + sanger sequencing Exome sequencing SNP array
Covered area Non-CDS and CDS CDS CDS
Follow up, m, median (range) 23.37 (0.23 to 157.83)
Status (alive/dead), n 22/19
  1. The bold values indicated that the proportion of TCL subtypes accounting for more than 10% of the sample
  2. AITL angioimmunoblastic T-cell lymphoma, ALCL anaplastic large cell lymphoma, ATLL adult T-cell lymphoma-leukemia, CDS coding sequence, COSMIC catalogue of somatic mutations in cancer, CTCL cutaneous T-cell lymphoma, EATL enteropathy-associated T-cell lymphoma, GDPH Guangdong Provincial People’s Hospital, HSTCL hepatosplenic T-cell lymphoma, JNU Jinan University, MEITL monomorphic epitheliotropic intestinal T-cell lymphoma, NGS next-generation sequencing, NKTCL NK-T-cell lymphoma, PCR polymerase chain reaction, PTCL-NOS peripheral T-cell lymphoma, not otherwise specified, SNP single nucleotide polymorphism, SPTCL subcutaneous panniculitis-like T-cell lymphoma, T-LBL T-lymphoblastic lymphoma, T-LGLL T-cell large granular lymphocytic leukemia
  3. aDue to rounding, not all percentages total 100%