|
Adverse event
|
Any grade
|
Grade I–II
|
Grade III–V
|
|---|
|
Any adverse event
|
37/94.9%
|
26/66.7%
|
11/28.2%
|
|
Rash
|
2/5.1%
|
2/5.1%
|
0/0.00%
|
|
Diarrhea
|
7/18.0%
|
6/15.4%
|
1/2.6%
|
|
Anemia
|
13/33.3%
|
10/25.6%
|
3/7.7%
|
|
Elevated transaminase
|
18/46.2%
|
9/23.1%
|
9/23.1%
|
|
Hypertension
|
3/7.7%
|
3/7.7%
|
0/0.00%
|
|
Leukopenia
|
4/10.3%
|
4/10.3%
|
0/0.00%
|
|
Hypothyroidism
|
6/15.4%
|
6/15.4%
|
0/0.00%
|
|
Bleeding
|
6/15.4%
|
6/15.38%
|
0/0.00%
|
|
Proteinuria
|
12/30.8%
|
11/28.2%
|
1/2.6%
|
|
Fever
|
1/2.6%
|
1/2.6%
|
0/0.00%
|
|
Fatigue
|
7/18.0%
|
7/18.0%
|
0/0.00%
|
|
Hand-foot skin reaction
|
6/15.4%
|
6/15.4%
|
0/0.00%
|
|
Dysphonia
|
1/2.6%
|
1/2.6%
|
0/0.00%
|
|
Decreased appetite
|
3/7.7%
|
3/7.7%
|
0/0.00%
|
|
Vomitting
|
1/2.6%
|
1/2.6%
|
0/0.00%
|
- Data are presented as n/%
